GForce Life Sciences
Executive Recruiter at GForce Life Sciences
DMPK Project Representative - Principal Research Scientist VI
12 month contract (possibility to convert to FTE)
On-site in Lexington, MA
Must be able to work on a W2
PURPOSE:
The Sr. Scientist will act as a DMPK project representative and provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. This will be achieved by proposing and leading internal and external research efforts to support project goals. The Sr. Scientist will work closely with pharmacology and medicinal chemistry team, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate novel chemical matter with drug-like properties. The Sr. Scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships with global ADME experts to leverage expertise and harmonize ADME strategy. The individual will be seen across the company and beginning to be viewed externally as a method/subject expert within small molecule DMPK.
TOP SKILLS PER MGR:
Project facing role (3+ years)
ADME or PKPD subject matter expert
Someone with relevant publications/abstracts that speak to metabolism/drug interaction/PKPD modeling
ESSENTIAL FUNCTIONS:
Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals
Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
Troubleshoot highly complex tasks through independent and team-based efforts
Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
Make independent decisions related to day-to-day experimental activities
Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
Ensure proper documentation of all experiments and data
Collaborative teamwork
Communicate regularly with international colleagues
Actively participate in cross-functional teams and meetings to drive project success
Achieve business goals, share learnings, knowledge and skills & promote cross-functional teamwork
Share knowledge & expertise to expand team capabilities and goals
Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
Write and review collaborative research manuscripts, project documents, and milestone documents
Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
Represent the organization as a subject matter expert by attending and presenting at scientific conferences and global meetings
QUALIFICATIONS:
Bachelor’s Degree within subject matter expertise required.
18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree with 6+ years’ post-doctoral and/or industry relevant experience can be considered.
Relevant required experience includes: Excellent understanding of ADME principles with knowledge of PK/PD modeling or biotransformation highly desirable
Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced model
Demonstrates excellent verbal and written communication skills.
Seniority Level
Mid-Senior level
Employment Type
Contract
Job function
Science, Research, and Project Management
Industries: Pharmaceutical Manufacturing
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12 month contract (possibility to convert to FTE)
On-site in Lexington, MA
Must be able to work on a W2
PURPOSE:
The Sr. Scientist will act as a DMPK project representative and provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. This will be achieved by proposing and leading internal and external research efforts to support project goals. The Sr. Scientist will work closely with pharmacology and medicinal chemistry team, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate novel chemical matter with drug-like properties. The Sr. Scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships with global ADME experts to leverage expertise and harmonize ADME strategy. The individual will be seen across the company and beginning to be viewed externally as a method/subject expert within small molecule DMPK.
TOP SKILLS PER MGR:
Project facing role (3+ years)
ADME or PKPD subject matter expert
Someone with relevant publications/abstracts that speak to metabolism/drug interaction/PKPD modeling
ESSENTIAL FUNCTIONS:
Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals
Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
Troubleshoot highly complex tasks through independent and team-based efforts
Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
Make independent decisions related to day-to-day experimental activities
Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
Ensure proper documentation of all experiments and data
Collaborative teamwork
Communicate regularly with international colleagues
Actively participate in cross-functional teams and meetings to drive project success
Achieve business goals, share learnings, knowledge and skills & promote cross-functional teamwork
Share knowledge & expertise to expand team capabilities and goals
Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
Write and review collaborative research manuscripts, project documents, and milestone documents
Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
Represent the organization as a subject matter expert by attending and presenting at scientific conferences and global meetings
QUALIFICATIONS:
Bachelor’s Degree within subject matter expertise required.
18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree with 6+ years’ post-doctoral and/or industry relevant experience can be considered.
Relevant required experience includes: Excellent understanding of ADME principles with knowledge of PK/PD modeling or biotransformation highly desirable
Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced model
Demonstrates excellent verbal and written communication skills.
Seniority Level
Mid-Senior level
Employment Type
Contract
Job function
Science, Research, and Project Management
Industries: Pharmaceutical Manufacturing
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