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Aphios Corporation

Fractional CFO

Aphios Corporation, North Reading, Massachusetts, United States, 01814

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Biotech IPO & Public-Markets Experience Required

North Reading, MA (Hybrid / On-site as needed)

Clinical-Stage Biotechnology | Capital Markets | Executive Leadership

Job Code: APH-2601-01

Aphios Corporation

is a clinical-stage biotechnology company advancing differentiated nanotechnology platforms and next-generation therapeutics across oncology, neurodegenerative disease, infectious disease, and substance-use disorder.

As the company enters its

next phase of growth and capital-markets readiness , Aphios is seeking an experienced

Part-Time / Fractional Chief Financial Officer (CFO)

with

direct biotech IPO and public-company preparation experience

to work closely with the CEO and Board.

This role is designed for a senior biotech finance executive who has

successfully guided companies through IPO preparation, public-company readiness, and alternative public-market pathways , and who is interested in a

high-impact, flexible leadership engagement

rather thanوقالت full-time operating role.

Key Responsibilities:

Lead financial strategy, capital planning, and cash-flow management for a growth-stage biotech

Prepare the company for

IPO and public-company readiness , including internal controls, reporting infrastructure, and governance

Oversee GAAP-compliant financial reporting, audit readiness, ಅಭ risk management

Develop and maintain long-range financial models aligned with clinical, regulatory, and commercialization milestones

Support

investor relations , Board communications, and external stakeholder engagement

Structure and evaluate

PIPE financings, crossover fund participation, and late-stage private capital strategies

Advise on

NASDAQ and NYSE uplisting requirements Bene ?

and readiness timelines

Evaluate

SPAC or de-SPAC-adjacent opportunities , as appropriate, without over-engineering the business

Interface with investment banks, auditors, securities counsel, and regulatory advisors

Oversee grant accounting and compliance (e.g., NIH, SBIR/STTR)

Qualifications:

Bachelor’s degree in Finance, Accounting, or related field (MBA, CPA, or CFA strongly preferred)

10–15+ years of senior financial leadership experience

in biotechnology or life sciences

Demonstrated experience taking a biotech company through IPO or IPO readiness

Strong working knowledge of

SEC reporting, GAAP, internal controls, and audit processes

Experience with

venture-backed, clinical-stage, or R&D-intensive organizations

Familiarity with

PIPEs, crossover investors, and public-market capital strategy

group?

Executive presence with the ability to engage effectively at the

Board and investor level

Comfortable operating in

lean, entrepreneurial environments

Why This Role?

High-impact executive position with

direct influence on capital-markets strategy

Flexible, part-time / fractional engagement suitable for seasoned CFOs

Opportunity to help position a differentiated biotech platform for

public-market execution

Mission-driven company with strong ESG alignment and meaningful therapeutic ambition

To Apply: Qualified candidates (or trusted referrals) should send a

resume and brief cover note

referencing

Job Code: APH-2601-01

to:

mail@aphios.com

www.aphios.com

No phone calls, please. Aphios Corporation is an equal opportunity employer.

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