Logo
Integrated Resources, Inc ( IRI )

Scientist - Oligonucleotide Synthesis

Integrated Resources, Inc ( IRI ), San Diego, California, United States, 92189

Save Job

Job Title

Recruitment Delivery Leader | Expert in Scientific & Clinical Hiring | Performance Mentor | Pharma/Biotech Talent Strategist Compensation

Integrated Resources, Inc (IRI) provided pay range. This range is provided by Integrated Resources, Inc (IRI). Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $52.00/hr - $52.00/hr About the Role

We are seeking a

highly motivated Scientist I

to join our Oligonucleotide Analytics team. In this role, you will play a critical part in advancing discovery and pre-portfolio projects by leveraging your expertise in

LC-MS, HPLC, and high-throughput oligonucleotide analytics . This is a

100% onsite role

in a fast-paced, innovative biopharma environment. Key Responsibilities

Operate

LC-MS systems

to perform in-process and final QC of highly modified oligonucleotides (siRNA, ASO). Optimize and improve

analytical methods

for novel oligonucleotide synthesis. Conduct project-specific analysis (GalNAc, Cholesterol, C16) using

denaturing/non-denaturing HPLC

and LC-MS. Establish and automate

high-throughput analytical capabilities

to align with synthesis throughput. Support QC for

lipid nanoparticle (LNP) formulations of mRNA . Collaborate with assay development and biology teams on integrity confirmation. Present data and project updates at group and departmental meetings. Qualifications

Ph.D. in Analytical Chemistry, Biochemistry, Nucleic Acid Chemistry, or related field with

1–3 years of postdoc/industry experience . Hands-on experience with

oligonucleotide or nucleoside/nucleotide characterization

is required. Strong expertise in

LC-MS and HPLC method development/optimization . Experience with

high-throughput automation

is strongly preferred. Seniority level

Mid-Senior level Employment type

Contract Job function

Other Industries

Pharmaceutical Manufacturing and Biotechnology Research We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

#J-18808-Ljbffr