ziprecruiter
Sr. Principal Scientist/Associate Director - Antibody Engineering
ziprecruiter, San Diego, California, United States, 92154
Overview
Sr. Principal Scientist / Associate Director – Antibody Engineering
Interested in learning more about this job Scroll down and find out what skills, experience and educational qualifications are needed. Location:
San Diego, CA Employment Type:
Full-time Hiring Company:
BioPhase (on behalf of our client) Pay:
$170,000–$190,000 base + bonus; stock options Hours:
Monday–Friday, full-time (no overtime) Responsibilities
Serve as subject-matter expert for protein/antibody engineering, formatting, and structure–function hypotheses. Lead, mentor, and develop protein engineering scientists; provide technical oversight. Act as project lead to deliver milestones across discovery programs. Collaborate with biology, computational, and development teams to progress hits into developable candidates. Design/build antibody & protein combinatorial libraries; plan and run engineering campaigns. Drive continuous improvement of lab workflows and data practices. Oversee curation/aggregation of experimental & in-silico data to inform predictive models. Contribute to platform/technology strategy with scientific leadership. Qualifications
MS/PhD in Biochemistry, Chemistry, or related field with 7+ years biopharma experience. Deep knowledge of protein structure, interactions, and physicochemical properties. Proven people leadership and experience managing scientists. Track record leading cross-functional programs from target validation through optimization to candidate nomination. Advanced understanding of multiple antibody formats (mAbs, bi/multispecifics, scFv, sdAbs, etc.). Extensive hands-on experience in antibody/protein engineering (humanization, liability removal, optimization). Familiarity with developability assessments (solubility, stability, manufacturability) and using them to guide design. Comfort with in-silico tools/programming/databases; exposure to ML-aided discovery a plus. Experience with plate-based assay development & high-throughput workflows. Engineering of small proteins/enzymes. Ability to synthesize structural/biophysical data (epitope mapping, kinetics, physicochemical profiling) for decisions. Benefits Comprehensive package including medical, dental, vision, life & insurance; 401(k) with match; PTO; parental leave; flexible schedule; relocation assistance (if applicable); year-end shutdown. Apply today and help us bring transformative biologics to patients!
#J-18808-Ljbffr
Sr. Principal Scientist / Associate Director – Antibody Engineering
Interested in learning more about this job Scroll down and find out what skills, experience and educational qualifications are needed. Location:
San Diego, CA Employment Type:
Full-time Hiring Company:
BioPhase (on behalf of our client) Pay:
$170,000–$190,000 base + bonus; stock options Hours:
Monday–Friday, full-time (no overtime) Responsibilities
Serve as subject-matter expert for protein/antibody engineering, formatting, and structure–function hypotheses. Lead, mentor, and develop protein engineering scientists; provide technical oversight. Act as project lead to deliver milestones across discovery programs. Collaborate with biology, computational, and development teams to progress hits into developable candidates. Design/build antibody & protein combinatorial libraries; plan and run engineering campaigns. Drive continuous improvement of lab workflows and data practices. Oversee curation/aggregation of experimental & in-silico data to inform predictive models. Contribute to platform/technology strategy with scientific leadership. Qualifications
MS/PhD in Biochemistry, Chemistry, or related field with 7+ years biopharma experience. Deep knowledge of protein structure, interactions, and physicochemical properties. Proven people leadership and experience managing scientists. Track record leading cross-functional programs from target validation through optimization to candidate nomination. Advanced understanding of multiple antibody formats (mAbs, bi/multispecifics, scFv, sdAbs, etc.). Extensive hands-on experience in antibody/protein engineering (humanization, liability removal, optimization). Familiarity with developability assessments (solubility, stability, manufacturability) and using them to guide design. Comfort with in-silico tools/programming/databases; exposure to ML-aided discovery a plus. Experience with plate-based assay development & high-throughput workflows. Engineering of small proteins/enzymes. Ability to synthesize structural/biophysical data (epitope mapping, kinetics, physicochemical profiling) for decisions. Benefits Comprehensive package including medical, dental, vision, life & insurance; 401(k) with match; PTO; parental leave; flexible schedule; relocation assistance (if applicable); year-end shutdown. Apply today and help us bring transformative biologics to patients!
#J-18808-Ljbffr