Brigham and Women's Hospital
Bioinformatic Research Assistant I
Brigham and Women's Hospital, Boston, Massachusetts, us, 02298
We are seeking a motivated and detail‑oriented Bioinformatics Research Assistant to support ongoing translational research projects focused on gene regulation, cancer biology, and hematopoiesis. The successful candidate will assist in analyzing large‑scale sequencing datasets and contribute to the development of computational tools for data interpretation and visualization.
Education
Bachelor’s degree (or current graduate student) in Bioinformatics, Computational Biology, Computer Science, or a related field.
Proficiency in R, Python, or similar programming languages for data analysis.
Experience
New grad with some relevant coursework.
0‑1 year preferred.
Can this role accept experience in lieu of a degree? Yes.
Knowledge, Skills, and Abilities
Familiarity with Linux/Unix environments and command‑line tools.
Basic understanding of molecular biology and genomics.
Good interpersonal and communication skills.
Careful attention to detail.
Excellent organizational skills and ability to prioritize a variety of tasks.
Computer literacy, including database tools.
Ability to follow directions and exhibit professionalism.
Key Responsibilities
Process and analyze next‑generation sequencing (NGS) data, including RNA‑seq, ATAC‑seq, ChIP‑seq, and related datasets.
Perform data cleaning, normalization, and statistical analysis.
Conduct differential expression and pathway enrichment analyses.
Integrate bioinformatics data with publicly available databases (e.g., TCGA, GEO, ENCODE).
Generate high‑quality figures and visualizations for presentations and manuscripts.
Maintain organized records of analyses, scripts, and results.
Collaborate with wet‑lab scientists to interpret computational findings in the context of experimental results.
Physical Requirements
Standing Occasionally (3-33%)
Walking Occasionally (3-33%)
Sitting Constantly (67-100%)
Lifting Occasionally (3-33%) 20lbs – 35lbs
Carrying Occasionally (3-33%) 20lbs – 35lbs
Pushing Rarely (Less than 2%)
Pulling Rarely (Less than 2%)
Climbing Rarely (Less than 2%)
Balancing Occasionally (3-33%)
Stooping Occasionally (3-33%)
Kneeling Rarely (Less than 2%)
Crouching Rarely (Less than 2%)
Crawling Rarely (Less than 2%)
Reaching Occasionally (3-33%)
Gross Manipulation (Handling) Constantly (67-100%)
Fine Manipulation (Fingering) Frequently (34-66%)
Feeling Constantly (67-100%)
Foot Use Rarely (Less than 2%)
Vision – Far Constantly (67-100%)
Vision – Near Constantly (67-100%)
Talking Constantly (67-100%)
Hearing Constantly (67-100%)
The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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Education
Bachelor’s degree (or current graduate student) in Bioinformatics, Computational Biology, Computer Science, or a related field.
Proficiency in R, Python, or similar programming languages for data analysis.
Experience
New grad with some relevant coursework.
0‑1 year preferred.
Can this role accept experience in lieu of a degree? Yes.
Knowledge, Skills, and Abilities
Familiarity with Linux/Unix environments and command‑line tools.
Basic understanding of molecular biology and genomics.
Good interpersonal and communication skills.
Careful attention to detail.
Excellent organizational skills and ability to prioritize a variety of tasks.
Computer literacy, including database tools.
Ability to follow directions and exhibit professionalism.
Key Responsibilities
Process and analyze next‑generation sequencing (NGS) data, including RNA‑seq, ATAC‑seq, ChIP‑seq, and related datasets.
Perform data cleaning, normalization, and statistical analysis.
Conduct differential expression and pathway enrichment analyses.
Integrate bioinformatics data with publicly available databases (e.g., TCGA, GEO, ENCODE).
Generate high‑quality figures and visualizations for presentations and manuscripts.
Maintain organized records of analyses, scripts, and results.
Collaborate with wet‑lab scientists to interpret computational findings in the context of experimental results.
Physical Requirements
Standing Occasionally (3-33%)
Walking Occasionally (3-33%)
Sitting Constantly (67-100%)
Lifting Occasionally (3-33%) 20lbs – 35lbs
Carrying Occasionally (3-33%) 20lbs – 35lbs
Pushing Rarely (Less than 2%)
Pulling Rarely (Less than 2%)
Climbing Rarely (Less than 2%)
Balancing Occasionally (3-33%)
Stooping Occasionally (3-33%)
Kneeling Rarely (Less than 2%)
Crouching Rarely (Less than 2%)
Crawling Rarely (Less than 2%)
Reaching Occasionally (3-33%)
Gross Manipulation (Handling) Constantly (67-100%)
Fine Manipulation (Fingering) Frequently (34-66%)
Feeling Constantly (67-100%)
Foot Use Rarely (Less than 2%)
Vision – Far Constantly (67-100%)
Vision – Near Constantly (67-100%)
Talking Constantly (67-100%)
Hearing Constantly (67-100%)
The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
#J-18808-Ljbffr